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Search Results for " hepatitis B "

ターゲット

125

阻害剤

45

天然化合物

12

リコンビナントタンパク質

3

ライブラリー

カタログ番号 製品名 別名 ターゲット
TP2231 HBcAg [Hepatitis B virus] (18-27) Others
HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person.
TP1520 Hepatitis B Virus Core (128-140) Hepatitis B Virus Core 128-140
The hepatitis B virus (HBV) core protein has been found in the nucleus, the cytoplasm, or both of HBV-infected hepatocytes. nuclear localization of the HBV core protein is negatively regulated by phosphorylation during t...
T23407 Surface antigen (208-215) [Hepatitis B Virus] Others
The nucleocapsid of the hepatitis B virus is covered by an envelope of HBV surface antigen (HBsAg), which has the common, group-specific determinant a. The four major subtypes of HBsAg, adw, adr, ayw and ayr, are generat...
T11669 IR415 HBV
T5832 Besifovir HBV
Besifovir, a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV).
T27527 HBF-0259 HBF 0259 Antiviral
HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV...
T16366 NVR 3-778 HBV
NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM belonging to the SBA class It has anti-HBV activity.
T20048 Vidarabine phosphate Antiviral
Vidarabine phosphate is an adenosine monophosphate analog. It is the monophosphate ester of VIDARABINE. It also has antiviral and possibly antineoplastic properties.
T4475 JNJ-632 HBV
JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator.
T11409 GLP-26 HBV
GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM...
TQ0017 AB-423 HBV
AB-423 is an inhibitor of HBV capsid assembly, and potently inhibits HBV replication (EC50/EC90: 0.08-0.27 μM/0.33-1.32 μM in cells).
T3449 Bay 41-4109 racemate HBV
BAY 41-4109 racemate is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
T6846 Vesatolimod GS-9620 Apoptosis , HCV Protease , HBV , TLR , HIV Protease
Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.
T15573 Inarigivir soproxil SB9200 HCV Protease
Inarigivir soproxil (SB9200) is an agonist of innate immunity. It also displays effective antiviral activity against resistant hepatitis C virus (HCV) variants (EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype ...
T0044 Oxethazaine Oxetacaine HBV , Sodium Channel
Oxethazaine (Oxetacaine), a topical anesthetic, is used to prevent acid-induced esophageal pain.
T3444 Merimepodib VX-497,VI-21497 Dehydrogenase , Antiviral , HCV Protease , HBV
Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).
T9225 Vebicorvir ABI-H0731 HBV
Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor, has demonstrated effective antiviral activity.
T4121 Bicyclol SY801 HBV , Autophagy
Bicyclol (SY801)(SY 801) is an anti-hepatitis drug. Oral administration of bicyclol normalizes the elevated serum transaminases (ALT, AST) by 50% in chronic viral hepatitis B and C, and also has a certain level of inhibi...
T12097 Morphothiadin GLS4 HBV
Morphothiadin (GLS4) is a potent inhibitor on the replication of both wild-type and adefovir-resistant HBV (IC50 of 12 nM).
T7447 Adefovir HBV , Reverse Transcriptase , Telomerase
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection.
T76527 Hepatitis B Virus Receptor Binding Fragment
Hepatitis B Virus Receptor Binding Fragment (hepatitis B peptide 4980), a synthetic peptide analog, specifically binds to Hep G2 cells and is a potential immunogen anticipated to induce protective antibodies through the ...
T0353 Osalmid Oxaphenamide,4'-Hydroxysalicylanilide HBV , DNA/RNA Synthesis
Osalmid (Oxaphenamide) is a choleretic drug, inhibits ribonucleotide reductase activity by targeting ribonucleotide reductase small subunit M2 (RRM2).
T1513 Telbivudine NV 02B,L-Thymidine,Epavudine Others , HBV , Reverse Transcriptase
Telbivudine (NV 02B) is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of telbivudine is as a Nucleoside Reverse Transcriptase Inhibitor. The chemical classification of tel...
T26674 AT-130 AT 130 HBV , DNA/RNA Synthesis
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging.
T12719 RG7834 RO 7020322 HBV
RG7834 (RO 7020322) is a highly selective and orally bioavailable inhibitor of HBV(HBsAg and HBeAg and HBV DNA with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells).
T8471 Vonafexor EYP001,PLX007,pxl007 FXR , HBV
Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects
T6446 Clevudine L-FMAU,Levovir HBV , DNA/RNA Synthesis
Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The ...
T9054 RO6889678 HBV
RO6889678 is HBV inhibitor with a complex ADME profile.
T4328 OSS_128167 SIRT6-IN-1 HBV , Sirtuin
OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 μM), SIRT1(IC50=1578 μM) and SIRT2(IC50=751 μM).
T0085L Entecavir BMS200475,SQ34676 HBV
Entecavir (SQ34676) is a guanosine nucleoside analogue used in the treatment of chronic hepatitis B virus (HBV) infection. Entecavir therapy can be associated with flares of the underlying hepatitis B during or after the...
T76528 Hepatitis b virus pre-s region (120-145)
Hepatitis B Virus Pre-S Region (120-145) is a preS2 peptide that effectively blocks the attachment of single-chain Fv fragment (scFv) or IgG to recombinant Hepatitis B surface antigen (r-HBsAg) [1].
T9518 Inarigivir ammonium ORI-9020 ammonium,SB-9200 ammonium HBV
Inarigivir ammonium (SB-9200 ammonium) is a dinucleotide antiviral compound that significantly reduces HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir is an agonist of retinoic acid-inducible gene-I (...
T6439 Cetylpyridinium Chloride Cetamium,Pristacin,Hexadecylpyridinium Chloride Others , HBV , Antibacterial
Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
T14489 Azvudine FNC,RO-0622 HCV Protease , HBV , HIV Protease , Reverse Transcriptase
Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1...
T22142 RO8191 RO4948191,CDM-3008 HCV Protease , HBV , JAK , IFNAR , STAT
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
T1649 Tenofovir PMPA,TDF,GS 1278 HBV , HIV Protease , Reverse Transcriptase
Tenofovir (GS 1278) is an adenine analog REVERSE TRANSC-RIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIV...
T83511 [Ala127] Hepatitis B Virus Pre-S Region (120-131)
[Ala127] Hepatitis B Virus Pre-S Region (120-131) is a peptide consisting of the sequence MQWNSTAFHQT, which may be utilized in studies focusing on enhancing activity [1].
T1646 Famciclovir BRL 42810 DNA/RNA Synthesis , HSV
Famciclovir (BRL 42810) is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DNA Polymerase Inhibitor.
T7111 Tenofovir Disoproxil GS 4331,Bis(POC)-PMPA HBV , HIV Protease , Reverse Transcriptase
Tenofovir Disoproxil (GS 4331) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
T1675 Adefovir dipivoxil Hepsera,GS 0840,Preveon Others , HBV , Reverse Transcriptase
Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficienc...
T0682 Lamivudine GR109714X,BCH-189 HIV Protease , Reverse Transcriptase
Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
T8498 EIDD-1931 Beta-d-N4-hydroxycytidine Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndr...
T2409L Tenofovir Disoproxil Fumarate GS-1278 Disoproxil Fumarate,Tenofovir DF HBV , HIV Protease , Reverse Transcriptase
Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug, fumaric acid salt form of tenofovir, a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir disoproxil fumarate is prescribe...
T0085 Entecavir monohydrate SQ 34676,BMS-200475,Entecavir hydrate HBV
Entecavir monohydrate (BMS-200475) is a selective inhibitor of the replication of the hepatitis B virus (HBV). It, a new deoxyguanine nucleoside analog.
T67904 Antiviral agent HBV
Antiviral agent is thiazolidin-4-one with anti-hepatitis B activity
T39043 Tenofovir amibufenamide HS-10234 HBV
Tenofovir amibufenamide (HS-10234) (HS-10234) is a Tenofovir prodrug, an antiviral compound with oral activity. Tenofovir amibufenamide inhibits hepatitis B virus (HBV) and can be used in chronic hepatitis B (CHB) studie...
T27221 DVR-01 3-(azepan-1-ylsulfonyl)-N-benzyl-4-chlorobenzamide HBV
DVR-01 is an HBV capsid inhibitor and can be used in studies about the treatment of Hepatitis B virus (HBV) infection and related conditions.
T64221 Linvencorvir RG7907 HBV , Antibiotic
Linvencorvir is a hepatitis B virus (HBV) core protein variant modifier used to treat chronic HBV infection.
T6214 Emtricitabine FTC,Emtriva,BW1592 HIV Protease , Reverse Transcriptase
Emtricitabine (FTC) (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B virus.
T77714 HBV-IN-37 HBV
HBV-IN-37 is an HBV inhibitor with an EC50 value of 10 μM and can be used for hepatitis B disease-related research.

Compounds

HBcAg [Hepatitis B virus] (18-27)
TP2231
Synonym:
Target: Others
Hepatitis B Virus Core (128-140)
TP1520
Synonym: Hepatitis B Virus Core 128-140
Target:
surface antigen (208-215) [Hepatitis B Virus]
T23407
Synonym:
Target: Others
IR415
T11669
Synonym:
Target: HBV
Besifovir
T5832
Synonym:
Target: HBV
HBF-0259
T27527
Synonym: HBF 0259
Target: Antiviral
NVR 3-778
T16366
Synonym:
Target: HBV
Vidarabine phosphate
T20048
Synonym:
Target: Antiviral
JNJ-632
T4475
Synonym:
Target: HBV
GLP-26
T11409
Synonym:
Target: HBV
AB-423
TQ0017
Synonym:
Target: HBV
Bay 41-4109 racemate
T3449
Synonym:
Target: HBV
Vesatolimod
T6846
Synonym: GS-9620
Target: Apoptosis, HCV Protease, HBV, TLR, HIV Protease
Inarigivir soproxil
T15573
Synonym: SB9200
Target: HCV Protease
Oxethazaine
T0044
Synonym: Oxetacaine
Target: HBV, Sodium Channel
Merimepodib
T3444
Synonym: VX-497,VI-21497
Target: Dehydrogenase, Antiviral, HCV Protease, HBV
Vebicorvir
T9225
Synonym: ABI-H0731
Target: HBV
Bicyclol
T4121
Synonym: SY801
Target: HBV, Autophagy
Morphothiadin
T12097
Synonym: GLS4
Target: HBV
Adefovir
T7447
Synonym:
Target: HBV, Reverse Transcriptase, Telomerase
Hepatitis B Virus Receptor Binding Fragment
T76527
Synonym:
Target:
Osalmid
T0353
Synonym: Oxaphenamide,4'-Hydroxysalicylanilide
Target: HBV, DNA/RNA Synthesis
Telbivudine
T1513
Synonym: NV 02B,L-Thymidine,Epavudine
Target: Others, HBV, Reverse Transcriptase
AT-130
T26674
Synonym: AT 130
Target: HBV, DNA/RNA Synthesis
RG7834
T12719
Synonym: RO 7020322
Target: HBV
Vonafexor
T8471
Synonym: EYP001,PLX007,pxl007
Target: FXR, HBV
Clevudine
T6446
Synonym: L-FMAU,Levovir
Target: HBV, DNA/RNA Synthesis
RO6889678
T9054
Synonym:
Target: HBV
OSS_128167
T4328
Synonym: SIRT6-IN-1
Target: HBV, Sirtuin
Entecavir
T0085L
Synonym: BMS200475,SQ34676
Target: HBV
Hepatitis b virus pre-s region (120-145)
T76528
Synonym:
Target:
Inarigivir ammonium
T9518
Synonym: ORI-9020 ammonium,SB-9200 ammonium
Target: HBV
Cetylpyridinium Chloride
T6439
Synonym: Cetamium,Pristacin,Hexadecylpyridinium Chloride
Target: Others, HBV, Antibacterial
Azvudine
T14489
Synonym: FNC,RO-0622
Target: HCV Protease, HBV, HIV Protease, Reverse Transcriptase
RO8191
T22142
Synonym: RO4948191,CDM-3008
Target: HCV Protease, HBV, JAK, IFNAR, STAT
Tenofovir
T1649
Synonym: PMPA,TDF,GS 1278
Target: HBV, HIV Protease, Reverse Transcriptase
[Ala127] Hepatitis B Virus Pre-S Region (120-131)
T83511
Synonym:
Target:
Famciclovir
T1646
Synonym: BRL 42810
Target: DNA/RNA Synthesis, HSV
Tenofovir Disoproxil
T7111
Synonym: GS 4331,Bis(POC)-PMPA
Target: HBV, HIV Protease, Reverse Transcriptase
Adefovir dipivoxil
T1675
Synonym: Hepsera,GS 0840,Preveon
Target: Others, HBV, Reverse Transcriptase
Lamivudine
T0682
Synonym: GR109714X,BCH-189
Target: HIV Protease, Reverse Transcriptase
EIDD-1931
T8498
Synonym: Beta-d-N4-hydroxycytidine
Target: Virus Protease, HCV Protease, SARS-CoV, Topoisomerase
Tenofovir Disoproxil Fumarate
T2409L
Synonym: GS-1278 Disoproxil Fumarate,Tenofovir DF
Target: HBV, HIV Protease, Reverse Transcriptase
Entecavir monohydrate
T0085
Synonym: SQ 34676,BMS-200475,Entecavir hydrate
Target: HBV
Antiviral agent
T67904
Synonym:
Target: HBV
Tenofovir amibufenamide
T39043
Synonym: HS-10234
Target: HBV
DVR-01
T27221
Synonym: 3-(azepan-1-ylsulfonyl)-N-benzyl-4-chlorobenzamide
Target: HBV
Linvencorvir
T64221
Synonym: RG7907
Target: HBV, Antibiotic
Emtricitabine
T6214
Synonym: FTC,Emtriva,BW1592
Target: HIV Protease, Reverse Transcriptase
HBV-IN-37
T77714
Synonym:
Target: HBV
1 2 3
カタログ番号 製品名 別名 ターゲット
TN1482 Chamaechromone P450 , HBV
Chamaechromone is a natural product isolated from the roots of Stellera chamaejasme L.. Chamaechromone has anti-HBV and insecticidal activity.
T4S1718 Punicalin HBV , HIV Protease
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM).
T3273 Bifendate Bifendatatum HBV , Reverse Transcriptase
Bifendate (Bifendatatum) is commonly used to treat the transaminase elevation that caused by viral hepatitis and drug-induced liver injury.
T1922 Pseudolaric Acid B Apoptosis , p38 MAPK , Ferroptosis , HBV , Autophagy , Antifungal
Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.
T2780 Catalpol Catalpinoside,Digitalis purpurea L Others , HBV
Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.
T3S0872 Paederoside Antiviral , HBV
1. Paederoside is a potent deterrent against the beetle was isolated from the aphid . 2. Paederoside displays high anti-tumor promoting activity against the Epstein-Barr virus activation.
T3810 Saikosaponin B2 Others , HCV Protease
Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces differentiation of B16 melanoma cells, with...
TQ0248 Alisol F HBV
Alisol F is a natural product from Alisma plantago-aquatica Linn and has many activities.
T5S2254 Swertianolin Bellidifolin-8-O-Glucoside Others , HBV , Antibacterial , AChE
1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin...
T3921 Punicalagin SARS-CoV , HBV
Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumula...
T3750 4-Hydroxyacetophenone 4-Acetylphenol,Piceol,p-Acetylphenol,4'-Hydroxyacetophenone HBV , Xanthine Oxidase
4-Hydroxyacetophenone (4-Acetylphenol) is a potent xanthine oxidase inhibitor.
T3815 Isoscopoletin 7-Methoxyesculetin,6-Hydroxy-7-methoxycoumarin Others , HBV
Isoscopoletin (7-Methoxyesculetin) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 6, 7-dimethoxy-2h-chromen-2-one.
T2848 Osthole Osthol,NSC 31868,Ostol Apoptosis , HBV , Parasite , Histamine Receptor
Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation.
T3001 Honokiol NSC 293100 ERK , HCV Protease , MEK , Akt , Autophagy
Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.
T0894 Thiamine hydrochloride Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride Apoptosis , HBV , Endogenous Metabolite
Thiamine hydrochloride (Vitamin B1) is the hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, Thiami...
T5098 Isochlorogenic acid A 3,5-CQA,3,5-Dicaffeoylquinic acid Reactive Oxygen Species , HBV , Endogenous Metabolite
Isochlorogenic acid A (3,5-Dicaffeoylquinic acid), a natural phenolic acid, exhibits antioxidant and anti-inflammatory properties.
T0392 Artemisinin Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,Artemisinine HCV Protease , Ferroptosis , Akt , Parasite
Artemisinin (Qinghaosu) is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of malarial organisms, including chloroquine-resistant Plasmodium ...
T2S1158 4,5-Dicaffeoylquinic acid 3,4-Dicaffeoylquinic acid,Isochlorogenic acid C Others , HBV , Endogenous Metabolite
1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity.
TN1034 Sennidin B HCV Protease , transporter , Akt , PI3K
Sennidin B stimulates glucose incorporation in rat adipocytes.
TN1033 Sennidin A HCV Protease , transporter , Akt , PI3K
Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM.
TN6732 Oenothein B Apoptosis , HCV Protease , Antibacterial , Antifungal
Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties.
T1020 Doxorubicin hydrochloride Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127 Apoptosis , Mitophagy , HBV , HIV Protease , Topoisomerase , Antibacterial , Antibiotic , AMPK , Autophagy
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitum...
T1456 Doxorubicin Hydroxydaunorubicin,Adriamycin Topoisomerase , AMPK
T6S1918 Schisantherin B Gomisin-B,Wuweizi ester-B,Schizantherin-B Beta Amyloid , Others
1. Schisantherin B (Schizantherin-B) shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.
T9371 DL-Pyroglutamic acid Others
DL-Pyroglutamic acid exhibited a strong inactivating effect on hepatitis B surface antigen.
TN2088 Platycodin D2 IL Receptor , HBV
Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as adjuvant eliciting Th1 and Th2 immune responses. Polygalaci...
TN4660 Niranthin Anti-infection , HBV , PAFR , Topoisomerase
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. N...
T4A2399 Cinobufotalin IL Receptor , Akt , MRP , P-gp
Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent...
TN1956 Mulberrofuran G Phosphatase , HBV , Glucosidase
Mulberrofuran G, isolated from Morus alba L., has anti-hepatitis B virus activity and protects against ischemic injury-induced cell death. Mulberrofuran G is a dual inhibitor of PTP1B and alpha-glucosidase for use in the...
T2754 Oxymatrine Oxysophoridine,Matrine N-oxide Influenza Virus , Autophagy , TGF-beta/Smad
Oxymatrine (Oxysophoridine) is an alkaloid isolated from Sophora flavescens, used as the antibiotic. It is a traditional Chinese medicine used in the treatment against hepatitis B virus.It can also inhibit iNOS expressio...
T2787 Picroside I 6'-Cinnamoylcatalpol MMP , STAT
Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug ...
T5S2343 Acetylshikonin Acetyl shikonin Others , P450 , AChE
1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang...
T3794 Pentagalloylglucose Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose Influenza Virus
1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten...
TMA0993 Ganoderic acid E Ganoderic acid F Antiviral
Ganoderic acid F has anti-hepatitis B, anti-inflammatory, and anti-tumor-promoting activities.
T26111 Robustaflavone
Robustaflavone is a naturally occurring biflavanoid isolated from Rhus succedanea and is a hepatitis B virus replication inhibitor.
TN2185 Schisantherin C Others
Schisantherin A, B, C, and D show good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.
TN4751 Periglaucine B HBV
Periglaucine B can inhibit hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells.
TN2417 Furomollugin Antifection
Furomollugin has antiviral activity, it can strongly suppress the secretion of hepatitis B surface antigen (HBsAg), with IC50 = 2.0 micrograms/mL, in human hepatoma Hep3B cells.
TN6458 Acetylshikonin
Acetylshikonin can effectively inhibit tumor cells, it can be used to treat hepatocellular carcinoma cells expressing hepatitis B virus X protein (HBX) by inducing ER stress , an oncoprotein from hepatitis B virus. Acety...
TN3012 4,5-Dihydroblumenol A HBV
4, 5-Dihydroblumenol shows significant inhibition against HepG2 cells transected with cloned hepatitis B virus DNA.
TN3687 Coclauril HBV
Coclauril shows anti-Hepatitis B virus (HBV) activities, with EC50 values of 7.6 ± 0.5 ug/mL.
TN4750 Periglaucine A HBV
Periglaucine A inhibits hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells.
TN1732 Herpetone HBV
Herpetone exhibits protective effects on CCl(4)-induced hepatocyte injury, it shows anti-hepatitis B virus (HBV) activity.
TN1815 Kadsulignan L HBV , PAFR
Kadsulignan L shows in vitro antiviral effects on hepatitis B virus. It also shows moderate platelet-activating factor (PAF) antagonistic activities with the IC50 value of 2.6 x 10(-5) M.
T79976 Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside HBV
Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside serves as an anti-hepatitis B virus (anti-HBV) agent, effectively inhibiting the secretion of HBV surface antigen (HBsAg) and HBV e antigen (HBeAg) in the Hep G2.2...

天然物製品

Chamaechromone
TN1482
Synonym:
Target: P450, HBV
Punicalin
T4S1718
Synonym:
Target: HBV, HIV Protease
Bifendate
T3273
Synonym: Bifendatatum
Target: HBV, Reverse Transcriptase
Pseudolaric Acid B
T1922
Synonym:
Target: Apoptosis, p38 MAPK, Ferroptosis, HBV, Autophagy, Antifungal
Catalpol
T2780
Synonym: Catalpinoside,Digitalis purpurea L
Target: Others, HBV
Paederoside
T3S0872
Synonym:
Target: Antiviral, HBV
Saikosaponin B2
T3810
Synonym:
Target: Others, HCV Protease
Alisol F
TQ0248
Synonym:
Target: HBV
Swertianolin
T5S2254
Synonym: Bellidifolin-8-O-Glucoside
Target: Others, HBV, Antibacterial, AChE
Punicalagin
T3921
Synonym:
Target: SARS-CoV, HBV
4-Hydroxyacetophenone
T3750
Synonym: 4-Acetylphenol,Piceol,p-Acetylphenol,4'-Hydroxyacetophenone
Target: HBV, Xanthine Oxidase
Isoscopoletin
T3815
Synonym: 7-Methoxyesculetin,6-Hydroxy-7-methoxycoumarin
Target: Others, HBV
Osthole
T2848
Synonym: Osthol,NSC 31868,Ostol
Target: Apoptosis, HBV, Parasite, Histamine Receptor
Honokiol
T3001
Synonym: NSC 293100
Target: ERK, HCV Protease, MEK, Akt, Autophagy
Thiamine hydrochloride
T0894
Synonym: Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride
Target: Apoptosis, HBV, Endogenous Metabolite
Isochlorogenic acid A
T5098
Synonym: 3,5-CQA,3,5-Dicaffeoylquinic acid
Target: Reactive Oxygen Species, HBV, Endogenous Metabolite
Artemisinin
T0392
Synonym: Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,Artemisinine
Target: HCV Protease, Ferroptosis, Akt, Parasite
4,5-Dicaffeoylquinic acid
T2S1158
Synonym: 3,4-Dicaffeoylquinic acid,Isochlorogenic acid C
Target: Others, HBV, Endogenous Metabolite
Sennidin B
TN1034
Synonym:
Target: HCV Protease, transporter, Akt, PI3K
Sennidin A
TN1033
Synonym:
Target: HCV Protease, transporter, Akt, PI3K
Oenothein B
TN6732
Synonym:
Target: Apoptosis, HCV Protease, Antibacterial, Antifungal
Doxorubicin hydrochloride
T1020
Synonym: Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127
Target: Apoptosis, Mitophagy, HBV, HIV Protease, Topoisomerase, Antibacterial, Antibiotic, AMPK, Autophagy
Doxorubicin
T1456
Synonym: Hydroxydaunorubicin,Adriamycin
Target: Topoisomerase, AMPK
Schisantherin B
T6S1918
Synonym: Gomisin-B,Wuweizi ester-B,Schizantherin-B
Target: Beta Amyloid, Others
DL-Pyroglutamic acid
T9371
Synonym:
Target: Others
Platycodin D2
TN2088
Synonym:
Target: IL Receptor, HBV
Niranthin
TN4660
Synonym:
Target: Anti-infection, HBV, PAFR, Topoisomerase
Cinobufotalin
T4A2399
Synonym:
Target: IL Receptor, Akt, MRP, P-gp
Mulberrofuran G
TN1956
Synonym:
Target: Phosphatase, HBV, Glucosidase
Oxymatrine
T2754
Synonym: Oxysophoridine,Matrine N-oxide
Target: Influenza Virus, Autophagy, TGF-beta/Smad
Picroside I
T2787
Synonym: 6'-Cinnamoylcatalpol
Target: MMP, STAT
Acetylshikonin
T5S2343
Synonym: Acetyl shikonin
Target: Others, P450, AChE
Pentagalloylglucose
T3794
Synonym: Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose
Target: Influenza Virus
Ganoderic acid E
TMA0993
Synonym: Ganoderic acid F
Target: Antiviral
Robustaflavone
T26111
Synonym:
Target:
Schisantherin C
TN2185
Synonym:
Target: Others
Periglaucine B
TN4751
Synonym:
Target: HBV
Furomollugin
TN2417
Synonym:
Target: Antifection
Acetylshikonin
TN6458
Synonym:
Target:
4,5-Dihydroblumenol A
TN3012
Synonym:
Target: HBV
Coclauril
TN3687
Synonym:
Target: HBV
Periglaucine A
TN4750
Synonym:
Target: HBV
Herpetone
TN1732
Synonym:
Target: HBV
Kadsulignan L
TN1815
Synonym:
Target: HBV, PAFR
Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside
T79976
Synonym:
Target: HBV

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-05822 Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His) HBV-D E. coli
Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of ...
TMPK-01492 HLA-A*02:01&B2M&HBV (FLLTRILTI) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity i...
TMPK-01501 HLA-A*02:01&B2M&HBV (FLLTRILTI) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity i...
TMPK-01491 HLA-A*02:01&B2M&HBV (FLLTRILTI) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity i...
TMPH-00810 Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc) HDV P. pastoris (Yeast)
Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging ...
TMPH-01632 MRC1 Protein, Human, Recombinant (His) Human E. coli
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens.; (Microbia...
TMPY-02810 Ninjurin-1 Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
Ninjurin-1, also known as NINJ1, is a member of the Ninjurin family of transmembrane (TM) proteins. It is expressed in CD19(+) CD10(+) B-cell progenitor cells and higher levels in B-lineage acute lymphoblastic leukemia c...
TMPY-02909 ASGR2 Protein, Human, Recombinant (His) Human HEK293 Cells
ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively ...
TMPJ-00420 CTLA-4 Protein, Mouse, Recombinant (Flag) Mouse HEK293 Cells
Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human. CTLA4 is similar to the T cell costimulatory pro...
TMPK-01413 H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi) Mouse HEK293 Cells
Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of...
TMPK-01416 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we...
TMPK-01412 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we...
カタログ番号 製品名
L1720 Nucleotide Compound Library

334 compounds
A unique collection of 334 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs;
L2193 Anti-Liver Cancer Compound Library

1787 compounds
1787 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies.
L6730 Anti-virus Traditional Chinese Medicine Monomer Library

268 compounds
A collection of 268 TCM monomers with anti-virus activity. An effective tool for drug development and pharmacological studies.